The Google Android Gingerbread operating system does not need any or much maintenance from the user if you just use the pre-installed Apps like web browsers, calculator, ebook reader, Kobo Bundled Apps, and install only a few Apps on your Kobo Vox. For the typical user who does not install a lot of Apps, it is typically not necessary to maintain their Vox except for updating it when Kobo sends a notification/pop-up Window to you on your Vox telling you a new Update is available, and updating Apps when the App maker sends you an e-mail or notification on his App telling you to update his App he made for Android.
Not having to run maintenance Apps on the Kobo Vox eReader Tablets is one of the best parts of owning a Google Android Tablet eReader compared to a Windows Tablet which needs an Anti-virus, firewall, and PC maintenance software because of the amount of viruses Windows has, and slow downs caused by Disk fragmentation, and temporary files which is mainly a Windows problem.
There are also no cooling fans, and hard drive to maintain on the Vox like a desktop or laptop computer, so all you need to do is use a clean piece of clothe to wipe fingerprints off the Vox's screen, buttons, sides, and back to keep it looking new.
The Kobo Vox does not need an Antivirus/Antispyware, Disk Defrag, Disk Cleanup, RAM Optimizers, Registry Cleaners, Firewall, System Utility Software, and any other type of maintenance software like Microsoft Windows because the Vox is uses Google Android Gingerbread mobile Operating System which is a secure operating system based on Linux which also don't need any computer maintenance software. I recommend reading reviews for Apps to see if it is a highly rated app which won't make your Tablet crash more often, or contains something fishy. Also, only download Apps from trusted Apps stores like GetJar, Amazon App Store, and Google Android Marketplace.
I read on forums, and blogs that Antivirus for Google Android can make the battery life worse, and make tablets and phones running Android feel slower, and might come with Ads pre-installed on it making your user experience bad because of spammy ads. Some Anti-virus even try to sell you expensive subscription, and the Anti-virus App is hard to uninstall.
The Kobo Vox eReader Tablet automatically notify you when new Updates are available when you are connected to Wi-Fi, so if you are on a reliable Wireless internet service, update your Vox, and while it is updating don't use, or touch your Vox until the Update is done, and the Vox eReader should automatically restart when Update is done.
The default GetJar marketplace for the Vox sometimes have some old Apps which are using an older version which do not have all the new features of the new versions, new levels and items if it is a game, and have some unfixed bugs, so you may need to use the Amazon App Store if you are in the US to get the latest version of an App which you installed on your Vox, or you can use a Google Android Smartphone or other tablet which has access to the Google Android Marketplace to download the APK, and use a MicroSD card, computer, e-mail, online storage, etc to sideload the newer version of the App to your Vox. Sometimes, you can update to the latest version of the App automatically when you first start up the App while your Vox is connected to the internet, and the App will automatically ask you if you want to update to the latest version, or automatically update to the latest version. You can also use the internet to search for the App makers e-mail, or contact info to see if they can send you the App APK file via E-mail, or a link to download it.
If you install a lot of Apps, it might slow down your Tablet or eReader if they are filling up your internal memory and also running in the Background when your Tablet starts up. To uninstall Apps you don't need, go to Settings then Applications, and click on Manage Apps where you can uninstall Apps which you don't need or want anymore. You can also "Move Apps to SD" if you don't want to uninstall the App, but want to increase the free space on your "Internal Memory" to make your start up faster if your tablet Internal Memory is full, and needs to be less full, and more empty. In the App info section for an App, you can also clear the Cache by hitting the Clear Cache Button which is usually safe to do since Cache files are just temporary files which gets created when you start an App. You can also "remove data" which will clear the App's save file, but not uninstall the App which might be useful if your save file for a game broke, or you want to restart a game from level 1 again. A microSD memory card will come in handy if your Vox is full of personal files like videos, music, PDF, pictures, etc which can take up a lot of disk space if you have a lot of personal files on your Vox.
You can also click on the running section on the applications menu, and see what Apps are running, if you notice every time a third party App you installed is running during start up, and you are not using it, and rarely use it, I recommend uninstalling it since it could make you have less free memory and CPU to run your current Apps. You can also use the Running section to stop Apps which crashed, or Apps which are still running after you closed the App a few minutes a go. You can stop the Rdio, INQ, and other Apps which come bundled with the Vox from running by holding down your fingers on them, and dragging them to the Trashcan which will appear on the bottom of the screen. You can also remove the Clock, Search Box, and Icons to Apps you don't need or want on your desktop. If you want them back you can just re-add them latter by holding down your finger on an empty part of the screen, and a Add wizard will appear which let you add Shortcuts, and widgets to your screens. You would also need to power off and power on Your Tablet to get rid of the running app in the memory sometimes.
Home Screen Desktop Widgets also might make your Tablet a little bit more slow if they use a lot of RAM or CPU power. You can drag and drop all the Widgets, and Icons you don't use to the trash can to save a little bit of space on your Tablet home screens, and not have them run when you start up your tablet. Plus, you have more space for the Widgets and shortcuts you want on your screen rather then stuff you don't use on your screen filling up space which can be better used.
You can also add Folders on your Homescreen to categorize and store your shortcuts in folders to save space.
With File Manager Apps like File Expert for Android, you can explore your Android SD Card and Micro SD card to delete old download files like .apk, .pdf, .mp3, etc which you downloaded from the web, or to better categorize them by making new folders and copying and pasting them into new folders. You can also move downloaded files to your MicroSD card which is a better idea then storing them on your Vox since you can more easily transfer files from a MicroSD to a computer, or other tablet with a MicroSD card reader, and if your Tablet won't turn on because it is out of battery power, and other problems, you can just take out the MicroSD card and use a laptop, desktop, or other tablet which can open MicroSD memory cards to read the files on it.
You can also manually delete old APK installer files you don't need after installation, or cut and paste them to a MicroSD Memory card inserted into your Vox's microSD memory slot with a File Manager software, or use the included USB cable which came with the Vox, and connect your computer to your Vox with the Bundled USB Cable for the Vox while both your Vox and computer is on. While your Vox is connected to your computer, it is a great chance for you to back up your other files which you downloaded from the internet to your Vox like videos, photos, documents, etc to your home computer for safe keeping.